Cayman DEPMPO-biotin

Name: Cayman DEPMPO-biotin
SKU: CAYM-13251-50
Price: 219.00 USD

List Price $219.00 Your Price $219.00

Cayman DEPMPO-biotin - CAYM (Additional S&H Or Hazmat Fees May Apply)

NETA PART: CAYM-13251-50

MFG.PART: 13251-50

UNSPSC: 12352200

Manufacturer: Cayman

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Description

Product Description

DEPMPO is a nitrone that is used to spin trap reactive O-, N-, S-, and C-centered radicals and allow their characterization when used in association with electron spin resonance. It is noted for the stability of adducts formed.¹ DEPMPO can be used in vitro or in vivo, as it crosses lipid bilayer membranes and is a good trapping agent in biological systems.^2,3 DEPMPO-biotin is a biotinylated form of DEPMPO which retains the outstanding persistency of its adducts.⁴ The biotin moiety offers an effective means for monitoring biodistribution in cells, tissues, and organs when used with an avidin-conjugated reporter. Importantly, DEPMPO-biotin binds free radicals, such as S-nitroso groups, on proteins, producing adducts that can be analyzed via the biotin tag. This direct labeling of S-nitrosothiols (SNO) thus serves as an effective alternative to the more cumbersome biotin-switch method for monitoring SNO formation.

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

N-[3-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]propyl]-[(2S,3R)-2-(diethoxyphosphinyl)-3,4-dihydro-2-methyl-1-oxido-2H-pyrrol-3-yl]methyl ester-carbamic acid

CAS Number

936224-52-1

Molecular Formula

C₂₄H₄₂N₅O₈PS

Formula Weight

591.7

Purity

≥95%

Formulation(Request formulation change)

A solution in ethanol

Solubility(Learn about Variance in Solubility)

Ethanol: 10 mg/mL
Water: 1 mg/mL

λ_max

202, 241 nm

SMILES

CCOP(=O)(OCC)C1(C)[C@H](COC(=O)NCCCNC(=O)CCCC[C@H]2SC[C@H]3NC(=O)N[C@@H]23)CC=[N+]1[O-]

InChi Code

InChI=1S/C24H42N5O8PS/c1-4-36-38(34,37-5-2)24(3)17(11-14-29(24)33)15-35-23(32)26-13-8-12-25-20(30)10-7-6-9-19-21-18(16-39-19)27-22(31)28-21/h14,17-19,21H,4-13,15-16H2,1-3H3,(H,25,30)(H,26,32)(H2,27,28,31)/t17-,18+,19-,21+,24?/m0/s1

InChi Key

UAQUUBGIOJZAFO-GLZOQUOBSA-N

Shipping & Storage Information

Storage

-80°C

Shipping

Dry ice in continental US; may vary elsewhere

Stability

≥ 2 years

Specifications

More Information
SKU	CAYM-13251-50
Supplier Part Number	13251-50
UM	EA
UNSPSC	12352200
Manufacturer	Cayman
MSDS URL	Click here
Temperature	-80
Refrigerated-Frozen	Y
CountryOfOrigin	United States
ProductLine	CAYM
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	5
Hazardous	Y
CAS Number	936224-52-1
Energy Star	No
Green	No
Controlled	N

Provide Content Correction

NETA PART NO.	Quantity

Cayman DEPMPO-biotin

Product Description

Technical Information

Shipping & Storage Information

Product Title