We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Piroxicam
List Price
$22.00
Your Price
$22.00
Cayman Piroxicam - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-13368-500
MFG.PART:
13368-500
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Piroxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties.1,2 It inhibits production of thromboxane B2 (TXB2; Item No. 19030) from arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) in HEL human erythroleukemic cells (IC50 = 0.45 µM), which endogenously express COX-1, as well as inhibits LPS-induced formation of prostaglandin F1α (PGF1α; Item No. 15010) from arachidonic acid in Mono-Mac-6 cells (IC50 = 0.77 µM), which endogenously express COX-2.2 Lornoxicam reduces LPS-induced production of nitric oxide and IL-6 in cell-based assays with IC50 values of 240 and ~470 µM, respectively. It reduces carrageenan-induced paw edema in rats when administered at doses of 1, 2.5, and 5 mg/kg.3 Formulations containing piroxicam have been used in the treatment of pain and inflammation associated with osteoarthritis and rheumatoid arthritis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-
CAS Number
36322-90-4
Synonyms
- NSC 666076
Molecular Formula
C15H13N3O4S
Formula Weight
331.4
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/mL
- DMSO: 20 mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
λmax
206, 240, 330 nm
SMILES
O=C(C(N1C)=C(O)C2=CC=CC=C2S1(=O)=O)NC3=CC=CC=N3
InChi Code
InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)
InChi Key
QYSPLQLAKJAUJT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-13368-500 |
|---|---|
| Supplier Part Number | 13368-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 36322-90-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |