Cayman HDAC11 Polyclonal Antibody

Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the ε-amino groups of lysines located near the amino termini of core histone proteins. Eleven members of HDAC family have been identified in the past several years.^, These HDAC family members are divided into two classes, I and II.The newest memeber of this family, HDAC11, has been cloned by Gao et Al. HDAC11 transcripts were limited to kidney, heart, brain, skeletal muscle, and testis. These results suggested that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo.

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