We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman S32826
List Price $42.00 Your Price $42.00
Cayman S32826 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-13664-1
MFG.PART: 13664-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Autotaxin is a lysophospholipase D, cleaving lysophosphatidylcholine to produce choline and lysophosphatidic acid (LPA). S32826 is a potent and selective inhibitor of autotaxin, inhibiting recombinant autotaxin β with an IC50 of 8.8 nM. It shows similar effectiveness against the three known autotaxin isoforms (α, β, and γ). It has no effect on a variety of receptors and enzymes, with the exceptions of src (IC50 = 6 μM) and phosphatase 1B (IC50 = 15 μM). S32826 inhibits LPA release from adipocytes (IC50 = 90 nM) and reduces plasma autotaxin activity by 57% when used at 5 μM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
P-[[4-[(1-oxo
CAS Number
1096770-84-1
Molecular Formula
C21H36NO4P
Formula Weight
397.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/mL
- DMSO: 2 mg/mL
λmax
250 nm
SMILES
O=C(CCCCCCCCCCCCC)NC1=CC=C(CP(O)(O)=O)C=C1
InChi Code
InChI=1S/C21H36NO4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-21(23)22-20-16-14-19(15-17-20)18-27(24,25)26/h14-17H,2-13,18H2,1H3,(H,22,23)(H2,24,25,26)
InChi Key
OUXAHVRWFHOKHY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-13664-1 |
|---|---|
| Supplier Part Number | 13664-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1096770-84-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |