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Cayman JNJ-10397049
List Price $54.00 Your Price $54.00
Cayman JNJ-10397049 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-14139-1
MFG.PART: 14139-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
JNJ-10397049 is a potent, selective, and bioavailable antagonist of the orexin-2 receptor (OX2R) (KB = 4.5 nM for OX2R versus 1.1 µM for OX1R).,, It has no significant affinity for over 50 other neurotransmitters or neuropeptide receptors. Applied subcutaneously to rats, JNJ-10397049 decreases the latency to persistent sleep and increases persistent sleep time. This compound produces a widespread attenuation of D-
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(2,4-dibromo
CAS Number
708275-58-5
Molecular Formula
C19H20Br2N2O3
Formula Weight
484.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 50 mg/mL
- DMF:PBS (pH 7.2) (1:4): 0.2 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
λmax
251 nm
SMILES
BrC1=CC(Br)=C(NC(N[C@@H]2[C@H](C3=CC=CC=C3)OC(C)(C)OC2)=O)C=C1
InChi Code
InChI=1S/C19H20Br2N2O3/c1-19(2)25-11-16(17(26-19)12-6-4-3-5-7-12)23-18(24)22-15-9-8-13(20)10-14(15)21/h3-10,16-17H,11H2,1-2H3,(H2,22,23,24)/t16-,17-/m0/s1
InChi Key
RBKIJGLHFFQHBE-IRXDYDNUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-14139-1 |
|---|---|
| Supplier Part Number | 14139-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 708275-58-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |