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Cayman ANA-12
List Price $37.00 Your Price $37.00
Cayman ANA-12 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-14309-1
MFG.PART: 14309-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
ANA-12 is a TrkB receptor antagonist that prevents activation of the receptor by BDNF with IC50 values of 45.6 nM and 41.1 μM for the high and low affinity sites of the receptor, respectively. It does not affect TrkA or TrkC in an assay of neurite outgrowth. Mice administered ANA-12 demonstrated reduced anxiety- and depression-related behaviors on a variety of tests predictive of anxiolytic and antidepressant properties in humans.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[2-[[(hexa
CAS Number
219766-25-3
Molecular Formula
C22H21N3O3S
Formula Weight
407.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- :
- DMF: 5 mg/mL
- DMSO: 5 mg/mL
λmax
247, 299, 315 nm
SMILES
O=C(NC1C(NCCCC1)=O)C2=CC=CC=C2NC(C3=CC4=C(C=CC=C4)S3)=O
InChi Code
InChI=1S/C22H21N3O3S/c26-20(25-17-10-5-6-12-23-21(17)27)15-8-2-3-9-16(15)24-22(28)19-13-14-7-1-4-11-18(14)29-19/h1-4,7-9,11,13,17H,5-6,10,12H2,(H,23,27)(H,24,28)(H,25,26)
InChi Key
TUSCYCAIGRVBMD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14309-1 |
|---|---|
| Supplier Part Number | 14309-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 219766-25-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |