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Cayman 5-Fluorouracil
List Price $324.00 Your Price $324.00
Cayman 5-Fluorouracil - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-14416-50
MFG.PART: 14416-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
5-Fluorouracil (5-FU) is a prodrug form of the thymidylate synthase inhibitor fluorodeoxyuridylate (FdUMP).1 It is also converted to the active metabolites FUTP and FdUTP, which induce RNA and DNA damage, respectively. In vivo, 5-FU (15 mg/kg) when administered in combination with docetaxel (Item No. 11637) reduces tumor growth in B88 and CAL 27 oral squamous cell carcinoma (OSCC) mouse xenograft models.2 Formulations containing 5-FU have been used in the treatment of colorectal, breast, gastric, and pancreatic cancers.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-
CAS Number
51-21-8
Synonyms
- 5-FU
- NSC 19893
- Ro 2-
9757 - U-
8953
Molecular Formula
C4H3FN2O2
Formula Weight
130.1
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 60 mg/mL
- DMSO: 53 mg/mL
- Ethanol: 0.8 mg/mL
- PBS (pH 7.2): 8 mg/mL
λmax
266 nm
SMILES
O=C1NC(NC=C1F)=O
InChi Code
InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
InChi Key
GHASVSINZRGABV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14416-50 |
|---|---|
| Supplier Part Number | 14416-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 51-21-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |