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Cayman I-Cbp112 (Hydrochloride); Purity- Greater Than Or Equal To
Product Description
Osthole is a coumarin that has been found in C. monnieri and has diverse biological activities.,, It decreases secretion of hepatitis B surface antigen (HBsAg) from Huh7 cells transfected with hepatitis B virus (HBV) DNA by 70% when used at a concentration of 20 µg/ml. Osthole induces bone morphogenetic protein 2 (BMP2) production in and differentiation of MG-63 and hFOB osteoblast-like cells. It induces vasorelaxation in isolated rat blood vessels, ileum, corpus cavernosum, and trachea. Osthole inhibits migration and invasion of MCF-7, MDA-MB-231, H1299, and A549 cancer cells in vitro and increases survival in an SMMC-7721 hepatocellular carcinoma mouse xenograft model. It also has hepatoprotective effects in mouse models of hepatitis induced by concanavalin A (Item No. ) and alcoholic fatty liver disease.
WARNING This product is not for human or veterinary use.
Technical Information
- 7-Methoxy-8-(3-methyl-2-butenyl)coumarin
- NSC 31868
- DMF: 25 mg/ml
- DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 20 mg/ml
Shipping & Storage Information
| SKU | CAYM-14468-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 14468-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 2147701-33-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |