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Cayman Src Kinase Inhibitor I
List Price
$591.00
Your Price
$591.00
Cayman Src Kinase Inhibitor I - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-14592-50
MFG.PART:
14592-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
The Src kinases constitute a family of non-receptor tyrosine kinases, which includes Src and Lck. Src kinase inhibitor I is a potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes.1,2 It less effectively blocks the receptor tyrosine kinases VEGFR2 and C-fms (IC50 = 0.32 and 30 µM), as well as a long list of serine/threonine kinases.1,2 Src kinase inhibitor I also inhibits receptor-interacting protein-2 with an IC50 value of 26 nM.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6,7-
CAS Number
179248-59-0
Molecular Formula
C22H19N3O3
Formula Weight
373.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 0.25 mg/mL
- DMF:PBS (pH 7.2) (1:2): 0.33 mg/mL
- DMSO: 2.5 mg/mL
λmax
223, 253, 344 nm
SMILES
COC1=C(OC)C=C(N=CN=C2NC3=CC=C(OC4=CC=CC=C4)C=C3)C2=C1
InChi Code
InChI=1S/C22H19N3O3/c1-26-20-12-18-19(13-21(20)27-2)23-14-24-22(18)25-15-8-10-17(11-9-15)28-16-6-4-3-5-7-16/h3-14H,1-2H3,(H,23,24,25)
InChi Key
DMWVGXGXHPOEPT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14592-50 |
|---|---|
| Supplier Part Number | 14592-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 179248-59-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |