Cayman MeOSuc-Ala-Ala-Pro-Val-AMC

Name: Cayman MeOSuc-Ala-Ala-Pro-Val-AMC
SKU: CAYM-14907-1
Price: 32.00 USD

List Price $32.00 Your Price $32.00

Cayman MeOSuc-Ala-Ala-Pro-Val-AMC - CAYM (Additional S&H Or Hazmat Fees May Apply)

NETA PART: CAYM-14907-1

MFG.PART: 14907-1

UNSPSC: 12352200

Manufacturer: Cayman

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Description

Product Description

MeOSuc-Ala-Ala-Pro-Val-AMC (MeOSuc-AAPV-AMC) is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase. The methoxy succinyl (MeO-Suc) peptide AAPV is avidly hydrolyzed by these elastases but not by cathepsin g.^, The addition of 7-amino-4-methylcoumarin (AMC) generates a peptide of low fluorescence (excitation: 355-380 nm; emission 440-460 nm) that demonstrates a linear increase in fluorescence in the presence of elastase. This peptidyl-AMC substrate detects as little as 11 pM human leukocyte elastase and 18 pM porcine pancreatic elastase.

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-valinamide

CAS Number

72252-90-5

Synonyms

I 1270
MeOSuc-AAPV-AMC
Methoxy Succinyl-Ala-Ala-Pro-Val-AMC

Molecular Formula

C₃₁H₄₁N₅O₉

Formula Weight

627.7

Purity

≥98%

Emission

440-460 nm

Excitation

355-380 nm

Formulation

A crystalline solid

Solubility

DMF: 20 mg/mL
DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL
DMSO: 16 mg/mL

λ_max

329 nm

SMILES

COC(CCC(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](C(C)C)C(NC2=CC=C(C(C)=CC(O3)=O)C3=C2)=O)=O)=O)C)=O)C)=O)=O

InChi Code

InChI=1S/C31H41N5O9/c1-16(2)27(30(42)34-20-9-10-21-17(3)14-26(39)45-23(21)15-20)35-29(41)22-8-7-13-36(22)31(43)19(5)33-28(40)18(4)32-24(37)11-12-25(38)44-6/h9-10,14-16,18-19,22,27H,7-8,11-13H2,1-6H3,(H,32,37)(H,33,40)(H,34,42)(H,35,41)/t18-,19-,22-,2

InChi Key

CMEUDEVBFFPSEI-NFHWZJRKSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 4 years

Specifications

More Information
SKU	CAYM-14907-1
Supplier Part Number	14907-1
UM	EA
UNSPSC	12352200
Manufacturer	Cayman
MSDS URL	Click here
Temperature	-20
Refrigerated-Frozen	Y
CountryOfOrigin	United States
ProductLine	CAYM
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	5
Hazardous	N
CAS Number	72252-90-5
Energy Star	No
Green	No
Controlled	N

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NETA PART NO.	Quantity

Cayman MeOSuc-Ala-Ala-Pro-Val-AMC

Product Description

Technical Information

Shipping & Storage Information

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