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Cayman Tigecycline
List Price $161.00 Your Price $161.00
Cayman Tigecycline - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-15026-10
MFG.PART: 15026-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Tigecycline is a broad-spectrum glycylcycline antibiotic that binds to the bacterial 30S ribosome, blocking the entry of transfer RNA, which halts protein synthesis and inhibits bacterial growth. It is active against a panel of 1,924 European clinical bacterial isolates including S. aureus, S. epidermidis, S. pneumoniae, E. faecalis, E. faecium, E. coli, K. pneumoniae, P. aeruginosa, and P. mirabilis strains (MICs = <1-32 μg/mL). In vivo, tigecycline (6.25 mg/kg twice daily for 5 days) decreases levels of C. difficile cytotoxin activity and spore formation in cecum and colon in a mouse model of C. difficile infection. Formulations containing tigecycline have been used in the treatment of a variety of bacterial infections.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4S,7-
CAS Number
220620-09-7
Synonyms
- GAR 936
- Glycylcycline
Molecular Formula
C29H39N5O8
Formula Weight
585.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 1 mg/mL
- PBS (pH 7.2): 10 mg/mL
λmax
251, 353 nm
SMILES
OC1=C(C(C2=C(O)[C@@](C(C(C(N)=O)=C(O)[C@H]3N(C)C)=O)(O)[C@@]3([H])C[C@]2([H])C4)=O)C4=C(N(C)C)C=C1NC(CNC(C)(C)C)=O
InChi Code
InChI=1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36,38-39,42H,8-9,11H2,1-7H3,(H2,30,41)(H,32,35)/t12-,14-,21-,29-/m0/s1
InChi Key
FPZLLRFZJZRHSY-HJYUBDRYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15026-10 |
|---|---|
| Supplier Part Number | 15026-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 220620-09-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |