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Cayman Tolterodine (tartrate)
List Price $178.00 Your Price $178.00
Cayman Tolterodine (tartrate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-15027-25
MFG.PART: 15027-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Tolterodine is an antagonist of muscarinic acetylcholine receptors (Kis = 1.4, 2.7, 3.6, 3.1, and 2.2 nM for M1-5 receptors, respectively).1 It reduces intracellular calcium mobilization induced by carbachol (carbamoylcholine; Item No. 14486) in bladder smooth muscle cells and submandibular gland cells isolated from cynomolgus monkeys (Kis = 3.16 and 2 nM, respectively).2 Tolterodine inhibits volume-induced bladder contractions and oxotremorine-induced salivation in rats (ID50s = 0.025 and 0.12 mg/kg, respectively).3 Formulations containing tolterodine have been used in the treatment of overactive bladder.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-
CAS Number
124937-52-6
Synonyms
- PNU 200583E
Molecular Formula
C22H31NO • C4H6O6
Formula Weight
475.6
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 0.1 mg/mL
- PBS (pH 7.2): 1 mg/mL
λmax
284 nm
SMILES
OC1=C([C@@H](C2=CC=CC=C2)CCN(C(C)C)C(C)C)C=C(C)C=C1.O[C@H]([C@@H](O)C(O)=O)C(O)=O
InChi Code
InChI=1S/C22H31NO.C4H6O6/c1-16(2)23(17(3)4)14-13-20(19-9-7-6-8-10-19)21-15-18(5)11-12-22(21)24;5-1(3(7)8)2(6)4(9)10/h6-12,15-17,20,24H,13-14H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t20-;/m1./s1
InChi Key
TWHNMSJGYKMTRB-VEIFNGETSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15027-25 |
|---|---|
| Supplier Part Number | 15027-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 124937-52-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |