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Cayman Torcetrapib
List Price
$151.00
Your Price
$151.00
Cayman Torcetrapib - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-15028-10
MFG.PART:
15028-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Torcetrapib is an inhibitor of cholesteryl ester transfer protein (CETP; IC50s = 47 and 51 nM for cholesteryl and triglyceride transfer, respectively). It is selective for CETP over phospholipid transfer protein (PLTP), lecithin:cholesterol acyltransferase (LCAT), and hepatic and lipoprotein lipases at 10 µM. Torcetrapib (30 mg/kg) inhibits CETP activity and increases HDL cholesterol levels in serum from transgenic mice expressing human CETP and ApoA1. It increases mean arterial blood pressure in Zucker fa/fa diabetic rats when administered at doses of 60 and 200 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4S-
CAS Number
262352-17-0
Synonyms
- CP 529,414
- (–)-Torcetrapib
Molecular Formula
C26H25F9N2O4
Formula Weight
600.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 10 mg/mL
λmax
251 nm
SMILES
O=C(OC)N(CC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)[C@H]2C[C@@H](CC)N(C(OCC)=O)C3=CC=C(C(F)(F)F)C=C32
InChi Code
InChI=1S/C26H25F9N2O4/c1-4-18-12-21(19-11-15(24(27,28)29)6-7-20(19)37(18)23(39)41-5-2)36(22(38)40-3)13-14-8-16(25(30,31)32)10-17(9-14)26(33,34)35/h6-11,18,21H,4-5,12-13H2,1-3H3/t18-,21+/m1/s1
InChi Key
CMSGWTNRGKRWGS-NQIIRXRSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15028-10 |
|---|---|
| Supplier Part Number | 15028-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 262352-17-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |