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Cayman Zd 7288; Purity- Greater Than Or Equal To 98%; Size- 50 Mg
List Price
$535.00
Your Price
$535.00
Cayman Zd 7288; Purity- Greater Than Or Equal To 98%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-15228-50
MFG.PART:
15228-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated (HCN) channels contribute to native pacemaker currents in heart and neurons and modulate cardiac and neuronal excitability.1 Certain HCN channels also accentuate neuropathic pain.2 ZD 7288 is a potent blocker of HCN channels that inhibits HCN4 more potently than HCN1 (IC50s = 32 and 158 nM, respectively).3 Through its effects on HCN channels, ZD 7288 modulates the sinoatrial node and slows heart rate.4,5 In addition, ZD 7288 reduces neuropathic pain in several animal models.6,7
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-pyrimidinamine, monohydrochloride
CAS Number
133059-99-1
Synonyms
- ICI-
D 7288
Molecular Formula
C15H21N4 • Cl
Formula Weight
292.8
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 50 mg/ml
- PBS (pH 7.2): 10 mg/ml
λmax
241, 285 nm
SMILES
CCN(C1=NC(C)=[N+](C)C(NC)=C1)C2=CC=CC=C2.[Cl-]
InChi Code
InChI=1S/C15H20N4.ClH/c1-5-19(13-9-7-6-8-10-13)15-11-14(16-3)18(4)12(2)17-15;/h6-11H,5H2,1-4H3;1H
InChi Key
DUWKUHWHTPRMAP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15228-50 |
|---|---|
| Featured | No |
| Supplier Part Number | 15228-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 133059-99-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |