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Cayman SB 204990
List Price $123.00 Your Price $123.00
Cayman SB 204990 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-15245-5
MFG.PART: 15245-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
SB 204990 is a cell-permeable prodrug form of SB 201076, an inhibitor of ATP citrate lyase.1 SB 204990 inhibits fatty acid and cholesterol synthesis in HepG2 cells in a concentration-dependent manner. Oral administration of SB 204990 (25 mg/kg) reduces plasma levels of the lipoproteins VLDL, LDL, and HDL by 21, 40, and 22%, respectively, in dogs. It also reduces VLDL synthesis and plasma cholesterol and triglyceride levels in rats in a dose-dependent manner.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3R,5S)-rel-5
CAS Number
154566-12-8
Molecular Formula
C18H22Cl2O5
Formula Weight
389.3
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMF:PBS(pH7.2) (1:2): 0.33 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 1 mg/mL
λmax
219 nm
SMILES
O=C1[C@](CC(O)=O)(O)C[C@@H](CCCCCCC2=CC=C(Cl)C=C2Cl)O1
InChi Code
InChI=1S/C18H22Cl2O5/c19-13-8-7-12(15(20)9-13)5-3-1-2-4-6-14-10-18(24,11-16(21)22)17(23)25-14/h7-9,14,24H,1-6,10-11H2,(H,21,22)/t14-,18+/m1/s1
InChi Key
YTRNLFYTHYWDAU-KDOFPFPSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15245-5 |
|---|---|
| Supplier Part Number | 15245-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 154566-12-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |