We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman R 1530
List Price $203.00 Your Price $203.00
Cayman R 1530 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-15255-10
MFG.PART: 15255-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
R 1530 is a multi-kinase inhibitor that targets over 20 kinases, including angiogenesis-related receptor tyrosine kinases (Kds = 61, 88, and 15 nM for FGFR1, PDGFRβ, and VEGFR2, respectively).1 It also inhibits FLT1, KIT, PLK4, and RET with Kd values of 9, 26, 11, and 22 nM, respectively.1 In cells, R 1530 delays mitosis, induces polyploidy, and blocks angiogenesis, ultimately promoting apoptosis or senescence.1,2 R 1530 strongly inhibits human tumor cell proliferation and reduces the growth of tumors in cancer xenograft models.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-(2-chloro
CAS Number
882531-87-5
Molecular Formula
C18H14ClFN4O
Formula Weight
356.8
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:7): 0.12 mg/mL
- Ethanol: 20 mg/mL
λmax
254, 395 nm
SMILES
COC(C(F)=C1)=CC2=C1C(C3=CC=CC=C3Cl)=NC4=C(C)NN=C4N2
InChi Code
InChI=1S/C18H14ClFN4O/c1-9-16-18(24-23-9)21-14-8-15(25-2)13(20)7-11(14)17(22-16)10-5-3-4-6-12(10)19/h3-8H,1-2H3,(H2,21,23,24)
InChi Key
UOVCGJXDGOGOCZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15255-10 |
|---|---|
| Supplier Part Number | 15255-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 882531-87-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |