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Cayman Q-VD-OPH
List Price
$138.00
Your Price
$138.00
Cayman Q-VD-OPH - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-15260-1
MFG.PART:
15260-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Q-VD-OPH is a broad-spectrum caspase inhibitor, blocking caspases-3, -7, -8, -9, -10, and -12 and inhibiting apoptosis when used at 10 µM., It more effectively inhibits apoptosis and is much less cytotoxic than Z-VAD-FMK (Item No. ) and Boc-D-FMK (Item No. )., Q-VD-OPH can be used in vivo, where it has been shown to prevent ischemia-reperfusion injury-induced apoptosis., This compound, by broadly inhibiting caspases, also promotes the differentiation of leukemic blasts cells, suggesting an application in differentiation therapy of certain forms of cancer.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3S)-5-(2,6- difluoro phenoxy)-3- [[(2S)-3- methyl-1-oxo- 2-[(2- quinolinyl carbonyl) amino]butyl] amino]-4-oxo- pentanoic acid
CAS Number
1135695-98-5
Synonyms
- Quinoline-Val
-Asp-Difluoro phenoxymethyl Ketone
Molecular Formula
C26H25F2N3O6
Formula Weight
513.5
Purity
≥95% (mixture of tautomers)
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS(pH 7.2) (1:4): 0.2 mg/mL
- Ethanol: 10 mg/mL
λmax
238, 289 nm
SMILES
O=C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(COC1=C(F)C=CC=C1F)=O)=O)C2=NC3=CC=CC=C3C=C2
InChi Code
InChI=1S/C26H25F2N3O6/c1-14(2)23(31-25(35)19-11-10-15-6-3-4-9-18(15)29-19)26(36)30-20(12-22(33)34)21(32)13-37-24-16(27)7-5-8-17(24)28/h3-11,14,20,23H,12-13H2,1-2H3,(H,30,36)(H,31,35)(H,33,34)/t20-,23-/m0/s1
InChi Key
OOBJCYKITXPCNS-REWPJTCUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15260-1 |
|---|---|
| Supplier Part Number | 15260-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1135695-98-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |