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Cayman Carmustine
List Price $84.00 Your Price $84.00
Cayman Carmustine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-15775-25
MFG.PART: 15775-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Carmustine is a DNA alkylating agent.1,2 It inhibits cell growth and induces cell cycle arrest at the g2/M phase in C6 rat glioma cells when used at a concentration of 10 µM.2 In vivo, carmustine (0.3 and 6.7 mg/kg per day) reduces tumor growth in a C6 rat glioma model. Carmustine (0.5 mg/kg, i.p.) also reduces the number of amyloid-β plaques and brain levels of amyloid-β (1-40) (Aβ40), as well as increases brain levels of soluble amyloid precursor protein (sAPP) in the APP/PS1 transgenic mouse model of Alzheimer’s disease.3 Formulations containing carmustine have been used in the treatment of gliomas and glioblastomas.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N,N-
CAS Number
154-93-8
Synonyms
- BCNU
- bis-Chloroethylnitrosourea
- NSC 409962
Molecular Formula
C5H9Cl2N3O2
Formula Weight
214.1
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 100 mm
- Ethanol: 100 mm
- Water: 25 mm
λmax
231 nm
SMILES
ClCCNC(N(N=O)CCCl)=O
InChi Code
InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
InChi Key
DLGOEMSEDOSKAD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15775-25 |
|---|---|
| Supplier Part Number | 15775-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 154-93-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |