We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman Sp-8-bromo-Cyclic AMPS (sodium salt)
List Price
$245.00
Your Price
$245.00
Cayman Sp-8-bromo-Cyclic AMPS (sodium salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-16002-1
MFG.PART:
16002-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Sp-8-bromo-cyclic AMPS (Sp-8-bromo-cAMPS) is a cell-permeable, cAMP analog that combines an exocyclic sulfur substitution in the axial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP., This configuration pools the structural features of two established cyclic-AMP-dependent protein kinase (PKA) activators, 8-bromo-cAMP (Item No. ) and Sp-cAMPS (Item No. ). Sp-8-bromo-cAMPS is a PKA agonist (EC50 = 1.5 µM) with improved lipophilicity and is not readily degraded by cyclic nucleotide phosphodiesterases.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
cyclic 3′,5′-
CAS Number
1573115-90-8
Synonyms
- 8-
Bromoadenosine 3,5- cyclic Monophosphothioate SP- Isomer - Sp-
8- bromo- cAMPS
Molecular Formula
C10H10BrN5O5PS • Na
Formula Weight
446.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 25 mg/mL
- Ethanol: 0.5 mg/mL
- PBS (pH 7.2): 10 mg/mL
λmax
212, 264 nm
SMILES
O[C@H]1[C@H](N2C(Br)=NC3=C2N=CN=C3N)O[C@H]4[C@H]1OP(OC4)([O-])=S.[Na+]
InChi Code
InChI=1S/C10H11BrN5O5PS.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(20-9)1-19-22(18,23)21-6;/h2-3,5-6,9,17H,1H2,(H,18,23)(H2,12,13,14);/q;+1/p-1/t3-,5-,6-,9-,22?;/m1./s1
InChi Key
SKJLJCVVXRNYGJ-QKAIHBBZSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16002-1 |
|---|---|
| Supplier Part Number | 16002-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Germany |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1573115-90-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |