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Cayman Prostaglandin F2α methyl ester
List Price $68.00 Your Price $68.00
Cayman Prostaglandin F2α methyl ester - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-16011-1
MFG.PART: 16011-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Prostaglandin F2α methyl ester (PGF2α methyl ester) is an analog of PGF2α in which the C-1 carboxyl group has been esterified as the methyl ester. PGF2α methyl ester was one of the first PG esters shown to have ocular hypotensive activity. This compound continues to be a standard by which other ocular hypotensive PG prodrugs are evaluated. The methyl ester is about 4-5 times more potent than the free acid, PGF2α. This difference is attributed to improved corneal penetration, and a depot effect of prolonged retention of the ester form of the compound in ocular tissue. A 2.5 µg dose of PGF2α-OMe applied to the eyes of cats results in a 6-8 mm Hg reduction in IOP.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
9α,11α,15S-
CAS Number
33854-16-9
Synonyms
- PGF2α methyl ester
Molecular Formula
C21H36O5
Formula Weight
368.5
Purity
≥98%
Formulation
A solution in methyl acetate
Solubility
- DMF: 35 mg/mL
- DMSO: 35 mg/mL
- Ethanol: 50 mg/mL
- Ethanol:PBS (pH 7.2) (1:4): 0.4 mg/mL
SMILES
CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(OC)=O
InChi Code
InChI=1S/C21H36O5/c1-3-4-7-10-16(22)13-14-18-17(19(23)15-20(18)24)11-8-5-6-9-12-21(25)26-2/h5,8,13-14,16-20,22-24H,3-4,6-7,9-12,15H2,1-2H3/b8-5-,14-13+/t16-,17+,18+,19-,20+/m0/s1
InChi Key
PJDMFGSFLLCCAO-NVRZHKMMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-16011-1 |
|---|---|
| Supplier Part Number | 16011-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 33854-16-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |