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Cayman NQDI-1
List Price $36.00 Your Price $36.00
Cayman NQDI-1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-16226-1
MFG.PART: 16226-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Apoptosis signal-regulating kinase 1 (ASK1) is the ubiquitously expressed mitogen-activated protein kinase kinase kinase 5 involved in a wide range of biological functions that are dependent on cell survival or death., NQDI-1 is a specific inhibitor of ASK1 (IC50 = 3 μM; Ki = 500 nM) that demonstrates potent selectivity against various serine/threonine and tyrosine protein kinases. It has been used to promote survival of induced pluripotent stem cell populations and to protect neurons from reactive oxygen species-induced apoptosis in a model of ischemia.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,7-dihydro-
CAS Number
175026-96-7
Molecular Formula
C19H13NO4
Formula Weight
319.3
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 1 mg/mL
- DMF:PBS(pH7.2) (1:2): 0.3 mg/mL
- DMSO: 1 mg/mL
λmax
217, 313, 334, 346, 402 nm
SMILES
O=C(C1=C2C(N3)=CC=C1)C4=CC=CC=C4C2=C(C(OCC)=O)C3=O
InChi Code
InChI=1S/C19H13NO4/c1-2-24-19(23)16-15-10-6-3-4-7-11(10)17(21)12-8-5-9-13(14(12)15)20-18(16)22/h3-9H,2H2,1H3,(H,20,22)
InChi Key
UFJGFNHRMPMALC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16226-1 |
|---|---|
| Supplier Part Number | 16226-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 175026-96-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |