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Cayman TDZD-8
List Price
$85.00
Your Price
$85.00
Cayman TDZD-8 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-16287-10
MFG.PART:
16287-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
TDZD-8 is a thiadiazolidine derivative that acts as a non-ATP competitive inhibitor of the serine/threonine kinase glycogen synthase kinase 3β (GSK3β; IC50 = 2 µM), binding to the active site of GSK3β. It does not significantly affect the activities of Cdk-1/cyclin B, CK-II, cAMP-dependent protein kinase, or protein kinase C (IC50s = >100 µM). TDZD-8 has been used to study the role of GSK3β during stem cell differentiation as well as in cell and animal models of Alzheimer’s disease and other neurodegenerative disorders.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-methyl-4-
CAS Number
327036-89-5
Synonyms
- GSK3β Inhibitor I
- NP 01139
Molecular Formula
C10H10N2O2S
Formula Weight
222.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 20 mg/mL
λmax
238 nm
SMILES
O=C1SN(C)C(N1CC2=CC=CC=C2)=O
InChi Code
InChI=1S/C10H10N2O2S/c1-11-9(13)12(10(14)15-11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3
InChi Key
JDSJDASOXWCHPN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16287-10 |
|---|---|
| Supplier Part Number | 16287-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 327036-89-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |