We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Ezetimibe; Purity- Greater Than Or Equal To 98%; Size- 50
List Price
$110.00
Your Price
$110.00
Cayman Ezetimibe; Purity- Greater Than Or Equal To 98%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-16331-50
MFG.PART:
16331-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Ezetimibe is an inhibitor of NPC1-like intracellular cholesterol transporter 1 (NPC1L1; Ki = 220 nM), a cholesterol transporter found in the apical membrane of enterocytes.1 It reduces cholesterol absorption in hamsters fed a high-cholesterol diet (ED50 = 0.04 mg/kg per day).2 Ezetimibe (346 nM) also reduces the levels of helper T cells and memory T cells isolated from the blood of heart transplant recipients.3 Formulations containing ezetimibe have been used in the treatment of primary hypercholesterolemia and mixed hyperlipidemia.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3R,4S)-1,4-fluorophenyl-3-[(3S-3-4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone
CAS Number
163222-33-1
Synonyms
- Ezetrol
- SCH 58235
Molecular Formula
C24H21F2NO3
Formula Weight
409.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/ml
- DMSO: 15 mg/ml
- Ethanol: 20 mg/ml
- Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
λmax
233 nm
SMILES
OC(C=C1)=CC=C1[C@@H]2[C@@H](CC[C@H](O)C3=CC=C(F)C=C3)C(N2C4=CC=C(F)C=C4)=O
InChi Code
InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
InChi Key
OLNTVTPDXPETLC-XPWALMASSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16331-50 |
|---|---|
| Featured | No |
| Supplier Part Number | 16331-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 163222-33-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |