Cayman 7-Keto Cholesterol; Purity- Greater Than Or Equal To 98%;

Tenidap is a COX-1 selective non-steroidal anti-inflammatory drug (IC₅₀s = <0.03, 1.2, and >30 µM for COX-1, COX-2, and 5-lipoxygenase (5-LO), respectively). It has anti-inflammatory and antirheumatic properties.^, In vitro, it inhibits prostaglandin D₂ (PGD₂), leukotriene B₄ (LTB₄), and prostaglandin E₂ (PGE₂) synthesis (IC₅₀s = 0.02, 18, and 32 µM, respectively).^, Tenidap also reversibly and dose-dependently activates hK_ir2.3 channels in CHO cells (EC₅₀ = 402 nM) and inhibits fatty acid amide hydrolase (FAAH) activity.^, A formulation containing tenidap was not approved for rheumatoid and osteoarthritis by the FDA due to adverse effects, including bone mineralization loss, as well as liver and kidney toxicity.

WARNING This product is not for human or veterinary use.