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Cayman SR 1078
List Price
$36.00
Your Price
$36.00
Cayman SR 1078 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-16503-1
MFG.PART:
16503-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Retinoic acid receptor-related orphan receptors α and γ (RORα and RORγ) have been demonstrated to play important roles in the regulation of metabolism, circadian rhythms, immune function, and tumorigenesis. SR 1078 is a selective agonist of RORα and RORγ that stimulates ROR transcriptional activity in HEK293 cell reporter assays at concentrations as low as 2 µM without effect at the related liver X receptors and farnesoid X receptors. At 5 µM, SR 1078 has been shown to stabilize p53 and to induce apoptosis in HepG2 cancer cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)-benzamide
CAS Number
1246525-60-9
Molecular Formula
C17H10F9NO2
Formula Weight
431.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/mL
- DMSO: 10 mg/mL
- Ethanol: 15 mg/mL
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
λmax
224, 273 nm
SMILES
O=C(NC1=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1)C2=CC=C(C(F)(F)F)C=C2
InChi Code
InChI=1S/C17H10F9NO2/C18-15(19,20)11-3-1-9(2-4-11)13(28)27-12-7-5-10(6-8-12)14(29,16(21,22)23)17(24,25)26/h1-8,29H,(H,27,28)
InChi Key
DUXWIYXHHGNUJU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16503-1 |
|---|---|
| Supplier Part Number | 16503-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1246525-60-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |