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Cayman D-Mannoheptulose; Purity- Greater Than Or Equal To 98%; Si
List Price
$92.00
Your Price
$92.00
Cayman D-Mannoheptulose; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-16548-10
MFG.PART:
16548-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Ledipasvir-d6 is intended for use as an internal standard for the quantification of ledipasvir (Item No. ) by GC- or LC-MS. Ledipasvir is an inhibitor of hepatitis C virus (HCV) non-structural protein 5A (NS5A)., It inhibits viral replication in genotype 1a and 1b HCV replicon cells (EC50s = 0.031 and 0.004 nM, respectively). It also inhibits viral replication in genotype 2a, 2b, 3a, 4a, 4d, 5a, 6a, and 6e HCV replicon cells (EC50s = 0.11-530 nM). Lepidasvir acts synergistically with IFN-α, ribavirin (Item No. ), or GS-9669 and additively with GS-9451, simeprevir (Item No. ), daclatasvir (Item No. ), or PSI-7977 (sofosbuvir; Item No. ) to inhibit viral replication in genotype 1a HCV replicon cells. Formulations containing ledipasvir have been used in combination therapy for the treatment of chronic HCV infection.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(1S)-1-
CAS Number
2050041-12-6
Molecular Formula
C49H48D6F2N8O6
Formula Weight
895.1
Purity
≥99% deuterated forms (d1-d6)
Formulation
A solid
Solubility
- DMSO: soluble
- Methanol: soluble
SMILES
FC(C1=C2C=CC(C(C=C3)=CC4=C3N=C([C@]5([H])[C@H](C6)CC[C@H]6N5C([C@@H](NC(OC([2H])([2H])[2H])=O)C(C)C)=O)N4)=C1)(C7=CC(C8=CN=C([C@@]9([H])N(C([C@@H](NC(OC([2H])([2H])[2H])=O)C(C)C)=O)CC%10(CC%10)C9)N8)=CC=C27)F
InChi Code
InChI=1S/C49H54F2N8O6/c1-24(2)39(56-46(62)64-5)44(60)58-23-48(15-16-48)21-38(58)42-52-22-37(55-42)28-9-13-32-31-12-8-26(18-33(31)49(50,51)34(32)19-28)27-10-14-35-36(20-27)54-43(53-35)41-29-7-11-30(17-29)59(41)45(61)40(25(3)4)57-47(63)65-6/h8-10,12-14,18-20,22,24-25,29-30,38-41H,7,11,15-17,21,23H2,1-6H3,(H,52,55)(H,53,54)(H,56,62)(H,57,63)/t29-,30+,38-,39-,40-,41-/m0/s1/i5D3,6D3
InChi Key
VRTWBAAJJOHBQU-NEKIOSTPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16548-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 16548-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United Kingdom |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 3615-44-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |