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Cayman 1-Methylnicotinamide (Chloride); Purity- Greater Than Or E
Product Description
Nicotinamide is a precursor of NAD (Item No. 16077) and NADP (Item No. 10004675), which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT; Item No. 15138).1 It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability.2,3 Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.4,5
WARNING This product is not for human or veterinary use.
Technical Information
- N1-Methylnicotinamide chloride
- Nicotinamide methochloride
- Trigonellamide chloride
- PBS (pH 7.2): 10 mg/ml
Shipping & Storage Information
| SKU | CAYM-16604-100 |
|---|---|
| Featured | No |
| Supplier Part Number | 16604-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1005-24-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |