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Cayman AT7867
List Price $196.00 Your Price $196.00
Cayman AT7867 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-16848-10
MFG.PART: 16848-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
AT7867 is a potent and orally bioavailable inhibitor of Akt isoforms Akt1, 2, and 3 (IC50s = 32, 17, and 47 nM, respectively). It also inhibits p70S6 kinase and PKA (IC50s = 85 and 20 nM, respectively), but is without effect against a panel of other kinases. AT7867 inhibits growth and induces apoptosis in a variety of cancer cell lines in vitro and suppresses tumor growth of PTEN-deficient xenografts in mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(4-chloro
CAS Number
857531-00-1
Molecular Formula
C20H20ClN3
Formula Weight
337.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: 0.33 mg/mL
λmax
258 nm
SMILES
ClC1=CC=C(C=C1)C2(CCNCC2)C3=CC=C(C4=CNN=C4)C=C3
InChi Code
InChI=1S/C20H20ClN3/c21-19-7-5-18(6-8-19)20(9-11-22-12-10-20)17-3-1-15(2-4-17)16-13-23-24-14-16/h1-8,13-14,22H,9-12H2,(H,23,24)
InChi Key
LZMOSYUFVYJEPY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16848-10 |
|---|---|
| Supplier Part Number | 16848-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 857531-00-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |