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Cayman Sch 202676 (Hydrobromide); Purity- Greater Than Or Equal T
List Price
$62.00
Your Price
$62.00
Cayman Sch 202676 (Hydrobromide); Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-16945-5
MFG.PART:
16945-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
GSK3179106 is an inhibitor of rearranged during transfection (RET) kinase (IC50 = 0.4 nM). It is selective for RET kinase over VEGF receptor 2 (VEGFR2/KDR; IC50 = 109 nM). GSK3179106 reduces the number of abdominal contractions induced by colorectal distension in acetic acid-sensitized rats when administered at a dose of 10 mg/kg twice per day.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(4-ethoxy-
CAS Number
1627856-64-7
Synonyms
- RET Kinase Inhibitor 1
Molecular Formula
C22H21F4N3O4
Formula Weight
467.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 50mg/mL
- DMSO: 50mg/mL
- DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL
- Ethanol: 25mg/mL
λmax
209, 233 nm
SMILES
O=C1C=C(OCC)C(C2=CC(F)=C(CC(NC3=NOC(C(C)(C)C(F)(F)F)=C3)=O)C=C2)=CN1
InChi Code
InChI=1S/C22H21F4N3O4/c1-4-32-16-9-19(30)27-11-14(16)12-5-6-13(15(23)7-12)8-20(31)28-18-10-17(33-29-18)21(2,3)22(24,25)26/h5-7,9-11H,4,8H2,1-3H3,(H,27,30)(H,28,29,31)
InChi Key
IDXKJSSOUXWLDB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16945-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 16945-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 265980-25-4 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |