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Cayman GSK650394
List Price
$218.00
Your Price
$218.00
Cayman GSK650394 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17001-10
MFG.PART:
17001-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
GSK650394 is an inhibitor of serum- and glucocorticoid-regulated kinase (IC50s = 62 and 103 nM for SGK1 and SGK2, respectively). It demonstrates greater than 30-fold selectivity for SGK1 over Akt and other related kinases. GSK650394 can inhibit the androgen-stimulated growth of human prostate carcinoma LNCaP cells with an IC50 value of ~ 1 μM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-benzoic acid
CAS Number
890842-28-1
Molecular Formula
C25H22N2O2
Formula Weight
382.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
λmax
241, 257, 295 nm
SMILES
O=C(O)C(C(C1CCCC1)=C2)=CC=C2C3=CNC4=NC=C(C5=CC=CC=C5)C=C43
InChi Code
InChI=1S/C25H22N2O2/c28-25(29)20-11-10-18(12-21(20)17-8-4-5-9-17)23-15-27-24-22(23)13-19(14-26-24)16-6-2-1-3-7-16/h1-3,6-7,10-15,17H,4-5,8-9H2,(H,26,27)(H,28,29)
InChi Key
WVSBGSNVCDAMCF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17001-10 |
|---|---|
| Supplier Part Number | 17001-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 890842-28-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |