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Cayman Sgc707; Purity- Greater Than Or Equal To 98%; Size- 50 Mg
List Price
$669.00
Your Price
$669.00
Cayman Sgc707; Purity- Greater Than Or Equal To 98%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17017-50
MFG.PART:
17017-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Protein arginine N-methyltransferase 3 (PRMT3, Item No. 11642) is a predominantly cytoplasmic enzyme that is constitutively expressed.1,2 SGC707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets. Developed by the Structural Genomics Consortium (SGC), SGC707 avidly binds PRMT3 (Kd = 50 nM by isothermal titration calorimetry) and inhibits the methylation of histones in cells with an IC50 value below 1 µM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-6-isoquinolinyl
CAS Number
1687736-54-4
Molecular Formula
C16H18N4O2
Formula Weight
298.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 2 mg/ml
- DMSO: 2 mg/ml
- Ethanol: 5 mg/ml
λmax
248, 294 nm
SMILES
O=C(NCC(N1CCCC1)=O)NC2=CC3=CC=NC=C3C=C2
InChi Code
InChI=1S/C16H18N4O2/c21-15(20-7-1-2-8-20)11-18-16(22)19-14-4-3-13-10-17-6-5-12(13)9-14/h3-6,9-10H,1-2,7-8,11H2,(H2,18,19,22)
InChi Key
DMIDPTCQPIJYFE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17017-50 |
|---|---|
| Featured | No |
| Supplier Part Number | 17017-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1687736-54-4 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |