Cayman Erythromycin A Enol Ether; Purity- Greater Than Or Equal T

The synthetic oleanane triterpenoid CDDO (Item No. ) is a Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells. The C-28 methyl ester of CDDO (CDDO methyl ester) blocks the cellular synthesis of inducible nitric oxide synthase (iNOS) and inducible COX-2 in INF-γ-activated mouse macrophages with an IC₅₀ value of 0.11 nM.^, It induces apoptosis, induces differentiation, and inhibits the inflammatory response in various tumor cells through inhibition of IκBα kinase/NF-κB signaling.^, CDDO methyl ester has potent antidiabetic activity, reducing proinflammatory cytokine expression in high fat diet-fed type 2 diabetic mice and in Lepr^db/db mice and triggering AMP-activated protein kinase and LKB1 activation in muscle and liver.

WARNING This product is not for human or veterinary use.