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Cayman Ic261; Purity- Greater Than Or Equal To 95%; Size- 25 Mg;
List Price
$420.00
Your Price
$420.00
Cayman Ic261; Purity- Greater Than Or Equal To 95%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17260-25
MFG.PART:
17260-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
IC261 is a reversible, ATP-competitive inhibitor of casein kinase 1 (CK1) that inhibits CK1δ and CK1ɛ (IC50 = ~1 µM for both), as well as CK1α (IC50 = 16 µM).1 It is at least 100-fold less effective against PKA, p34cdc2, and p55fyn.1 IC 261, at 1 µM, inhibits cytokinesis in primary mouse embryo fibroblasts.2 IC261 is used to elucidate the role of CK1 in cells and in whole organisms.3,4,5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,3-dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one
CAS Number
186611-52-9
Synonyms
- SU5607
Molecular Formula
C18H17NO4
Formula Weight
311.3
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
- Ethanol: 0.5 mg/ml
λmax
255, 358 nm
SMILES
COC1=C(/C=C2C(NC3=C/2C=CC=C3)=O)C(OC)=CC(OC)=C1
InChi Code
InChI=1S/C18H17NO4/c1-21-11-8-16(22-2)14(17(9-11)23-3)10-13-12-6-4-5-7-15(12)19-18(13)20/h4-10H,1-3H3,(H,19,20)/b13-10+
InChi Key
JBJYTZXCZDNOJW-JLHYYAGUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17260-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 17260-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 186611-52-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |