Cayman Lp44 (Hydrochloride); Purity- Greater Than Or Equal To 98%

Name: Cayman Lp44 (Hydrochloride); Purity- Greater Than Or Equal To 98%
SKU: CAYM-17287-1
Price: 44.00 USD

List Price $44.00 Your Price $44.00

Cayman Lp44 (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)

NETA PART: CAYM-17287-1

MFG.PART: 17287-1

UNSPSC: 12352200

Manufacturer: Cayman

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Description

Product Description

The apelin gene encodes a preproprotein that is processed to generate a variety of bioactive peptides, including those having 36, 17, or 13 amino acids (apelin-36, apelin-17, and apelin-13, respectively). The apelin proteins are the endogenous ligands of the G protein-coupled receptor, APJ.^, Apelin-36 is the full-length mature peptide produced from the translated 77 amino acid prepropeptide. The apelins act primarily in the peripheral and central nervous system, playing important roles in regulating cardiovascular function, fluid homeostasis, hypertension, and insulin sensitivity. Apelin-36 is a less potent agonist of APJ than either apelin-17 or apelin-13 (EC₅₀ = 20, 2.5, and 0.37 nM, respectively).^, Apelin-36 potently inhibits HIV-1 entry into cells expressing APJ and CD4, limiting HIV infection.

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

L-leucyl-L-valyl-L-glutaminyl-L-prolyl-L-arginylglycyl-L-seryl-L-arginyl-L-asparaginylglycyl-L-prolylglycyl-L-prolyl-L-tryptophyl-L-glutaminylglycylglycyl-L-arginyl-L-arginyl-L-lysyl-L-phenylalanyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine, trifluoroacetate salt

Molecular Formula

C₁₈₄H₂₉₇N₆₉O₄₃S • XCF₃COOH

Formula Weight

4195.8

Purity

≥95%

Amino Acids

LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF

Formulation

A crystalline solid

Peptide Sequence

LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF

Solubility

DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 10 mg/ml
PBS (pH 7.2): 10 mg/ml

SMILES

[H]N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N1CCC[C@H]1C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(NCC(N2CCC[C@H]2C(NCC(N3CCC[C@H]3C(N[C@H](C(N[C@@H](CCC(N)=O)C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N4CCC[C@H]4C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCCN)C(NCC(N5CCC[C@H]5C(N[C@H](C(N6CCC[C@H]6C(N[C@H](C(O)=O)CC7=CC=CC=C7)=O)=O)CCSC)=O)=O)=O)=O)CC8=CN=CN8)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC9=CC=CC=C9)=O)=O)=O)=O)=O)=O)=O)CC%10=CNC%11=C%10C=CC=C%11)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

InChi Code

InChI=1S/C184H297N69O43S.C2HF3O2/c1-98(2)80-106(187)147(266)247-146(100(5)6)172(291)239-120(58-61-138(190)258)174(293)252-77-32-53-133(252)169(288)235-109(42-20-65-209-177(192)193)148(267)220-91-142(262)226-128(95-254)164(283)232-115(47-25-70-214-182(202)203)157(276)243-126(86-139(191)259)151(270)222-93-143(263)248-73-28-50-130(248)166(285)223-94-145(265)250-75-30-52-132(250)168(287)244-124(84-103-87-217-107-39-15-14-38-105(103)107)162(281)233-117(56-59-136(188)256)150(269)219-89-140(260)218-90-141(261)225-110(43-21-66-210-178(194)195)152(271)229-112(44-22-67-211-179(196)197)153(272)228-111(41-17-19-64-186)156(275)241-123(82-101-34-10-8-11-35-101)161(280)231-114(46-24-69-213-181(200)201)154(273)230-113(45-23-68-212-180(198)199)155(274)234-118(57-60-137(189)257)159(278)237-119(49-27-72-216-184(206)207)173(292)251-76-31-54-134(251)170(289)236-116(48-26-71-215-183(204)205)158(277)240-122(81-99(3)4)160(279)246-129(96-255)165(284)242-125(85-104-88-208-97-224-104)163(282)227-108(40-16-18-63-185)149(268)221-92-144(264)249-74-29-51-131(249)167(286)238-121(62-79-297-7)175(294)253-78-33-55-135(253)171(290)245-127(176(295)296)83-102-36-12-9-13-37-102;3-2(4,5)1(6)7/h8-15,34-39,87-88,97-100,106,108-135,146,217,254-255H,16-33,40-86,89-96,185-187H2,1-7H3,(H2,188,256)(H2,189,257)(H2,190,258)(H2,191,259)(H,208,224)(H,218,260)(H,219,269)(H,220,267)(H,221,268)(H,222,270)(H,223,285)(H,225,261)(H,226,262)(H,227,282)(H,228,272)(H,229,271)(H,230,273)(H,231,280)(H,232,283)(H,233,281)(H,234,274)(H,235,288)(H,236,289)(H,237,278)(H,238,286)(H,239,291)(H,240,277)(H,241,275)(H,242,284)(H,243,276)(H,244,287)(H,245,290)(H,246,279)(H,247,266)(H,295,296)(H4,192,193,209)(H4,194,195,210)(H4,196,197,211)(H4,198,199,212)(H4,200,201,213)(H4,202,203,214)(H4,204,205,215)(H4,206,207,216);(H,6,7)/t106-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,146-;/m0./s1

InChi Key

GTDTUUTXIDWMQY-NAMWIFIASA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 4 years

Specifications

More Information
SKU	CAYM-17287-1
Featured	No
Supplier Part Number	17287-1
UM	EA
UNSPSC	12352200
Manufacturer	Cayman
MSDS URL	Click here
Temperature	-20
Refrigerated-Frozen	Refrigerated
CountryOfOrigin	United States
ProductLine	CAYM
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	2
Hazardous	N
CAS Number	824958-12-5
Energy Star	No
Green	No
ACT Ecolabel	No
Controlled	N

Provide Content Correction

NETA PART NO.	Quantity

Cayman Lp44 (Hydrochloride); Purity- Greater Than Or Equal To 98%

Product Description

Technical Information

Shipping & Storage Information

Product Title