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Cayman Imd 0354; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
List Price
$81.00
Your Price
$81.00
Cayman Imd 0354; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17290-5
MFG.PART:
17290-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
SMIFH2 is an inhibitor of formin homology 2 (FH2) domains. It inhibits assembly of profilin-actin mediated by mouse formin mDia1(FH1FH2) with an IC50 value of approximately 15 μM. It also inhibits actin assembly mediated by FH1FH2 constructs of mDia2, C. elegans CYK-1, S. pombe Cdc12 or Fus1, or S. cerevisiae Bni1. SMIFH2 (25 μM) disassembles formin-dependent actin cables and contractile rings, but not Arp2/3-dependent actin patches, in fission yeast. It is cytotoxic to NIH3T3 fibroblasts (IC50 = 28 μM). SMIFH2 (10 μM) increases and decreases the percentage of NIH3T3 cells with thin and thick F-actin bundles, respectively.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-(3-bromo
CAS Number
340316-62-3
Molecular Formula
C15H9BrN2O3S
Formula Weight
377.2
Purity
≥98% (mixture of isomers)
Formulation
A solid
Solubility
- DMSO: 100 mM
SMILES
O=C1NC(N(C2=CC(Br)=CC=C2)C(/C1=C/C3=CC=CO3)=O)=S
InChi Code
InChI=1S/C15H9BrN2O3S/c16-9-3-1-4-10(7-9)18-14(20)12(13(19)17-15(18)22)8-11-5-2-6-21-11/h1-8H,(H,17,19,22)/b12-8+
InChi Key
MVFJHEQDISFYIS-XYOKQWHBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17290-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 17290-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 978-62-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |