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Cayman Sb-705498; Purity- Greater Than Or Equal To 98%; Size- 10
List Price
$117.00
Your Price
$117.00
Cayman Sb-705498; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17313-10
MFG.PART:
17313-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
The transient receptor potential vanilloid type 1 (TRPV1) receptor is a nonselective cation channel gated by noxious heat, protons, and capsaicin (Item No. 92350). SB-705498 is an orally bioavailable, competitive antagonist of the capsaicin-mediated activation of TRPV1 receptors (pKis = 7.6, 7.5, and 7.3 for human, rat, and guinea pig, respectively).1 It has been shown to induce rapid, reversible inhibition of capsaicin (IC50 = 3 nM)-, acid (pH 5.3)-, or heat (50°C; IC50 = 6 nM)-mediated activation of human TRPV1 (at -70 mV).1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(2-bromophenyl)-
CAS Number
501951-42-4
Molecular Formula
C17H16BrF3N4O
Formula Weight
429.2
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/ml
- DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml
- DMSO: 16 mg/ml
- Ethanol: 10 mg/ml
λmax
257, 312 nm
SMILES
BrC1=C(NC(N[C@@H]2CCN(C3=NC=C(C(F)(F)F)C=C3)C2)=O)C=CC=C1
InChi Code
InChI=1S/C17H16BrF3N4O/c18-13-3-1-2-4-14(13)24-16(26)23-12-7-8-25(10-12)15-6-5-11(9-22-15)17(19,20)21/h1-6,9,12H,7-8,10H2,(H2,23,24,26)/t12-/m1/s1
InChi Key
JYILLRHXRVTRSH-GFCCVEGCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17313-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 17313-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 501951-42-4 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |