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Cayman Nitro Blue Tetrazolium (Chloride); Size- 5 G
Product Description
Bax inhibitor peptide V5 is an inhibitor of Bax. It decreases levels of the pro-apoptotic proteins Bax, Bad, and NF-ĸB p65 and increases levels of the anti-apoptotic proteins X-linked inhibitor of apoptosis (XIAP) and Bcl-2 in isolated mouse pancreatic islets when used at a concentration of 100 µM. It inhibits apoptosis induced by etoposide (Item No. ) in Hep3B human hepatoma cells when used at a concentration of 200 µM. Bax inhibitor peptide V5 (5 mg/ml, i.c.v.) decreases infarct volume and reduces ipsilateral paw preference in the cylinder rearing test, indicating an improvement in sensorimotor function, in a neonatal mouse model of hypoxic-ischemia brain injury induced by carotid artery ligation. Bax inhibitor peptide V5, when used at a concentration of 100 µM in syngeneic pancreatic islet cells prior to transplantation, inhibits increases in blood glucose levels in an intraperitoneal glucose tolerance test and increases survival in a mouse model of diabetes induced by streptozotocin (STZ; Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
- BIP V5
- VPMLK
- DMF: 15 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 20 mg/ml
- PBS (pH 7.2): 10 mg/ml
Shipping & Storage Information
| SKU | CAYM-17341-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 17341-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 298-83-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |