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Cayman Empagliflozin; Purity- Greater Than Or Equal To 98%; Size-
List Price
$333.00
Your Price
$333.00
Cayman Empagliflozin; Purity- Greater Than Or Equal To 98%; Size- 100 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17375-100
MFG.PART:
17375-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Empagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor (IC50 = 3.1 nM for the human transporter).1 It is selective for SGLT2 over SGLT1, -4, -5, and -6 (IC50s = 8.3, 11, 1.1, and 2 µM, respectively). Dietary administration of empagliflozin (0.03% for 10 weeks) reduces non-fasting blood glucose levels, as well as aortic superoxide levels and cardiac interstitial fibrosis, in db/db mice.2 It also decreases the severity of glomerulosclerosis, as well as reduces the escape latency in the Morris water maze, in the same model. Formulations containing empagliflozin have been used in the treatment of type 2 diabetes.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(1S)-1,5-
CAS Number
864070-44-0
Synonyms
- BI 10773
Molecular Formula
C23H27ClO7
Formula Weight
450.9
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
λmax
224 nm
SMILES
ClC(C=CC([C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)=C2)=C2CC3=CC=C(O[C@@H]4COCC4)C=C3
InChi Code
InChI=1S/C23H27ClO7/c24-18-6-3-14(23-22(28)21(27)20(26)19(11-25)31-23)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21-,22+,23-/m0/s1
InChi Key
OBWASQILIWPZMG-QZMOQZSNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17375-100 |
|---|---|
| Featured | No |
| Supplier Part Number | 17375-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 864070-44-0 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |