Cayman Chrysin; Purity- Greater Than Or Equal To 95%; Size- 5 G;

Vatiquinone is a metabolite of α-tocotrienol (Item No. ) that has antioxidant and ferroptosis inhibitory activity.^, It inhibits decreases in cell viability induced by the γ-glutamylcysteine synthetase inhibitor L-buthionine-(S,R)-sulfoximine (BSO; Item No. ) in primary fibroblasts isolated from patients with the mitochondrial diseases Friedreichs ataxia or Leigh syndrome (EC₅₀s = 24 and 30 nM, respectively). Vatiquinone inhibits cell death and lipid peroxidation induced by the glutathione peroxidase 4 (GPX4) inhibitor RSL3 in primary fibroblasts isolated from patients with the mitochondrial encephalopathic epilepsy disease pontocerebellar hypoplasia type 6 (PCH6; EC₅₀s = 17.3-21.8 and 33.1-57.6 nM, respectively).

WARNING This product is not for human or veterinary use.