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Cayman Ac-Ietd-Afc; Purity- Greater Than Or Equal To 95%; Size- 1
List Price
$44.00
Your Price
$44.00
Cayman Ac-Ietd-Afc; Purity- Greater Than Or Equal To 95%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17480-1
MFG.PART:
17480-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Ac-IETD-AFC is a fluorogenic substrate that can be cleaved by caspase-8 and related enzymes that recognize the amino acid sequence IETD, including caspase-3 processing enzyme, caspase-10, and granzyme B. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine, trifluoroacetate salt
Synonyms
- N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin
Molecular Formula
C31H38F3N5O12 • XCF3COOH
Formula Weight
729.7
Purity
≥95%
Emission
505 nm
Excitation
400 nm
Formulation
A crystalline solid
Solubility
- DMSO: 10 mg/ml
λmax
232, 340 nm
SMILES
OC(C[C@H](NC(C(NC([C@@H](NC([C@H]([C@@H](C)CC)NC(C)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)C(NC(C=C1O2)=CC=C1C(C(F)(F)F)=CC2=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C31H38F3N5O12.C2HF3O2/c1-5-13(2)25(35-15(4)41)29(49)37-19(8-9-22(42)43)27(47)39-26(14(3)40)30(50)38-20(12-23(44)45)28(48)36-16-6-7-17-18(31(32,33)34)11-24(46)51-21(17)10-16;3-2(4,5)1(6)7/h6-7,10-11,13-14,19-20,25-26,40H,5,8-9,12H2,1-4H3,(H,35,41)(H,36,48)(H,37,49)(H,38,50)(H,39,47)(H,42,43)(H,44,45);(H,6,7)/t13-,14+,19-,20-,25-,26?;/m0./s1
InChi Key
YWNQGRLHYRWGIP-FKXNOZCSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17480-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 17480-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |