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Cayman Pka Inhibitor Fragment (6-22) Amide; Size- 5 Mg
List Price
$502.00
Your Price
$502.00
Cayman Pka Inhibitor Fragment (6-22) Amide; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17486-5
MFG.PART:
17486-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3). It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC50 = 0.06 µM). It is selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 µM. CXCR3 antagonist 6c inhibits CXCR3-mediated migration of isolated human T cells (IC50 = ~100 nM).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[2-[(3- chlorobenzoyl) amino]-4-[[[2- (2,4-dichloro phenyl)ethyl] amino]carbonyl] phenyl]-N- ethylhexahydro- 1H-1,4- diazepine-1- carboxamide
CAS Number
870998-13-3
Molecular Formula
C30H32Cl3N5O3
Formula Weight
617.0
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: >100mM
SMILES
ClC1=CC=CC(C(NC2=CC(C(NCCC3=C(Cl)C=C(Cl)C=C3)=O)=CC=C2N4CCCN(C(NCC)=O)CC4)=O)=C1
InChi Code
InChI=1S/C30H32Cl3N5O3/c1-2-34-30(41)38-14-4-13-37(15-16-38)27-10-8-22(18-26(27)36-29(40)21-5-3-6-23(31)17-21)28(39)35-12-11-20-7-9-24(32)19-25(20)33/h3,5-10,17-19H,2,4,11-16H2,1H3,(H,34,41)(H,35,39)(H,36,40)
InChi Key
VPDHCRDNIQTCFU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17486-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 17486-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 121932-06-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |