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Cayman Cytosporone B; Purity- Greater Than Or Equal To 95%; Size-
List Price
$243.00
Your Price
$243.00
Cayman Cytosporone B; Purity- Greater Than Or Equal To 95%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17501-10
MFG.PART:
17501-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Cytosporone B is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM).1 Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene for Nur77 itself.1 Signaling through Nur77 induces apoptosis in cancer cells and retards xenograft tumor growth.1 It also induces genes related to gluconeogenesis and decreases atherosclerosis progression in mice fed a high fat and high cholesterol diet.1,2 Cytosporone B is brain penetrant and aggravates early brain injury in rats when given (13 mg/kg intraperitoneally) after experimentally-induced subarachnoid hemorrhage.3 Cytosporone B also has antibacterial properties.4,5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3,5-
CAS Number
321661-62-5
Synonyms
- Csn-B
- Dothiorelone G
Molecular Formula
C18H26O5
Formula Weight
322.4
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 50 mg/ml
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
λmax
220, 270, 300 nm
SMILES
OC1=CC(CC(OCC)=O)=C(C(CCCCCCC)=O)C(O)=C1
InChi Code
InChI=1S/C18H26O5/c1-3-5-6-7-8-9-15(20)18-13(11-17(22)23-4-2)10-14(19)12-16(18)21/h10,12,19,21H,3-9,11H2,1-2H3
InChi Key
UVVWQQKSNZLUQA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17501-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 17501-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 321661-62-5 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |