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Cayman Ku-60019; Purity- Greater Than Or Equal To 98%; Size- 25 M
List Price
$262.50
Your Price
$262.50
Cayman Ku-60019; Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17502-25
MFG.PART:
17502-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Avanafil-13C-d3 is intended for use as an internal standard for the quantification of avanafil (Item No. ) by GC- or LC-MS. Avanafil is an orally bioavailable inhibitor of phosphodiesterase 5 (PDE5; IC50 = 5.2 nM)., It is selective for PDE5 over PDE6, PDE1-4, and PDE7-11 (IC50s = 630, >5,000, and >5,000 nM, respectively). Avanafil (300 µg/kg, i.v.) potentiates pelvic nerve stimulation-induced penile tumescence in anesthetized dogs. Formulations containing avanafil have been used in the treatment of erectile dysfunction.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[[(3-chloro- 4-(methoxy- 13C-d3)phenyl) methyl]amino]- 2-[(2S)-2- (hydroxy methyl)-1- pyrrolidinyl]- N-(2-pyrimi dinylmethyl)- 5-pyrimidine carboxamide
CAS Number
2738376-89-9
Molecular Formula
C22[13C]H23ClD3N7O3
Formula Weight
488.0
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Solubility
- DMSO: Soluble
- Methanol: Soluble
SMILES
ClC(C=C1CNC2=NC(N3CCC[C@H]3CO)=NC=C2C(NCC4=NC=CC=N4)=O)=C(C=C1)O[13C]([2H])([2H])[2H]
InChi Code
InChI=1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1/i1+1D3
InChi Key
WEAJZXNPAWBCOA-PFMZXWIMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17502-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 17502-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 925701-46-8 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |