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Cayman Bgp-15; Purity- Greater Than Or Equal To 95%; Size- 25 Mg
List Price
$530.00
Your Price
$530.00
Cayman Bgp-15; Purity- Greater Than Or Equal To 95%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17503-25
MFG.PART:
17503-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis.1 BGP-15 is a PARP inhibitor and insulin sensitizer. In perfused heart, it blocks self-ADP-ribosylation of nuclear PARP (Ki = 57 µM) and mono-ADP-ribosylation of GRP78, resulting in decreased levels of reactive oxygen species, lipid peroxidation, and single-strand DNA breaks.2,3 BGP-15 acts as a co-inducer of heat shock protein 72, augmenting expression induced by heat shock factor 1 in adipocytes and skeletal muscles and improving insulin sensitivity.4,5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[2-hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide, dihydrochloride
CAS Number
66611-37-8
Molecular Formula
C14H22N4O2 • 2HCl
Formula Weight
351.3
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 0.25 mg/ml
- PBS (pH 7.2): 5 mg/ml
λmax
257, 277 nm
SMILES
N=C(NOCC(O)CN1CCCCC1)C2=CC=CN=C2.Cl.Cl
InChi Code
InChI=1S/C14H22N4O2.2ClH/c15-14(12-5-4-6-16-9-12)17-20-11-13(19)10-18-7-2-1-3-8-18;;/h4-6,9,13,19H,1-3,7-8,10-11H2,(H2,15,17);2*1H
InChi Key
ISGGVCWFTPTHIX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17503-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 17503-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 66611-37-8 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |