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Cayman Mcc950; Purity- Greater Than Or Equal To 98%; Size- 5 Mg;
List Price
$336.00
Your Price
$336.00
Cayman Mcc950; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17510-5
MFG.PART:
17510-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
NSC 95397 is a 1,4-naphthoquinone-based irreversible inhibitor of Cdc25 dual-specificity phosphatases, with Ki values of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively. It displays >125-fold selectivity for Cdc25 over VH1-related dual-specificity phosphatase and protein tyrosine phosphatase 1b. NSC 95397 significantly inhibits the growth of human and murine carcinoma cells, blocking G2/M phase transition., In rat liver epithelial cells, NSC 95397 induces cell cycle arrest, which is associated with phosphorylation of EGFR, activation of ERK1/2, phosphorylation of connexin43, and downregulation of gap junctional intercellular communication.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,3-bis[(2-
CAS Number
93718-83-3
Synonyms
- Cdc25 Inhibitor IV
- PTP Inhibitor XXIX
Molecular Formula
C14H14O4S2
Formula Weight
310.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml
- Ethanol: 0.33 mg/ml
λmax
240, 274, 452 nm
SMILES
O=C1C(SCCO)=C(SCCO)C(C2=CC=CC=C21)=O
InChi Code
InChI=1S/C14H14O4S2/c15-5-7-19-13-11(17)9-3-1-2-4-10(9)12(18)14(13)20-8-6-16/h1-4,15-16H,5-8H2
InChi Key
MAASHDQFQDDECQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17510-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 17510-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 210826-40-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |