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Cayman Trans-Ned-19; Purity- Greater Than Or Equal To 98%; Size-
List Price
$193.00
Your Price
$193.00
Cayman Trans-Ned-19; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17527-5
MFG.PART:
17527-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective concentration able to increase the enzyme by 150%) of 1 µM. It less potently activates SIRT2 and SIRT3 (EC150s = 25 and 50 µM, respectively). BML-278 induces hypoacetylation on α-tubulin in U937 cells that are pretreated with SAHA (Item No. ), a histone deacetylase inhibitor. It arrests cell cycling at the G1/S phase, reduces senescence in primary human mesenchymal cells, and significantly increases mitochondrial density in murine C2C12 myoblasts.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,4-dihydro-
CAS Number
120533-76-8
Molecular Formula
C24H25NO4
Formula Weight
391.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 12.5 mg/ml
- DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml
- DMSO: 3 mg/ml
λmax
226, 368 nm
SMILES
O=C(OCC)C1=CN(CC2=CC=CC=C2)C=C(C(OCC)=O)C1C3=CC=CC=C3
InChi Code
InChI=1S/C24H25NO4/c1-3-28-23(26)20-16-25(15-18-11-7-5-8-12-18)17-21(24(27)29-4-2)22(20)19-13-9-6-10-14-19/h5-14,16-17,22H,3-4,15H2,1-2H3
InChi Key
JOHFECBOWRGWJZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17527-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 17527-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1354235-96-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |