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Cayman Ms37452; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
List Price
$184.00
Your Price
$184.00
Cayman Ms37452; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17533-10
MFG.PART:
17533-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
INK128 is an inhibitor of TORC1/2, acting as an ATP-dependent inhibitor of mTOR kinase (IC50 = 1 nM).,, It blocks the phosphorylation of downstream substrates of both TORC1 and TORC2. INK128 interferes with the growth of cell lines which are resistant to rapamycin and pan-PI3K inhibitors., Moreover, daily, oral administration of INK128 inhibits angiogenesis and tumor growth in several xenograft models. The effects of INK128 on gene expression also reduce invasion and metastasis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-
CAS Number
1224844-38-5
Synonyms
- MLN0128
Molecular Formula
C15H15N7O
Formula Weight
309.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 1 mg/ml
- DMSO: 2 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
λmax
205, 243, 292 nm
SMILES
CC(C)N1C2=NC=NC(N)=C2C(C3=CC(N=C(N)O4)=C4C=C3)=N1
InChi Code
InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
InChi Key
GYLDXIAOMVERTK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17533-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 17533-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 423748-02-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |