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Cayman Ms37452; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
List Price
$111.00
Your Price
$111.00
Cayman Ms37452; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17533-5
MFG.PART:
17533-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Chromobox homolog 7 (CBX7) functions through its N-terminal chromodomain, which recognizes histone 3 trimethyl lysine 27 (H3K27me3), to repress gene transcription. It plays a key role in gene transcription in cellular processes related to stem cell self-renewal and differentiation, as well as tumor progression.1 MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).1 At 250 µM, it has been shown to derepress transcription of the polycomb repressive complex target gene p16/CDKN2A in prostate cancer cells.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[4-(2,3-dimethoxybenzoyl)-1-piperazinyl]-2-(3-methylphenoxy)-ethanone
CAS Number
423748-02-1
Molecular Formula
C22H26N2O5
Formula Weight
398.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
SMILES
COC1=CC=CC(C(N2CCN(C(COC3=CC(C)=CC=C3)=O)CC2)=O)=C1OC
InChi Code
InChI=1S/C22H26N2O5/c1-16-6-4-7-17(14-16)29-15-20(25)23-10-12-24(13-11-23)22(26)18-8-5-9-19(27-2)21(18)28-3/h4-9,14H,10-13,15H2,1-3H3
InChi Key
LUMCNRKHZRYQOV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17533-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 17533-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 423748-02-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |