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Cayman Nicardipine (Hydrochloride); Purity- Greater Than Or Equal
List Price
$169.00
Your Price
$169.00
Cayman Nicardipine (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 10 G; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17537-10
MFG.PART:
17537-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Nicardipine is a dihydropyridine L-type calcium channel antagonist that displays antihypertensive and antianginal activity.1 It is reported to inhibit adenosine A1, A2A, and A3 receptors with Ki values of 19.6, 63.8, and 3.25 µM, respectively, and can inhibit cytochrome P450 3A4 catalytic activity with an IC50 value of 0.148 µM.2,3 Additionally, nicardipine has been shown to activate transient receptor potential A1 channels, producing an increase in Ca2+ (EC50 = 0.5 µM).4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-methyl 5-[2-[methyl(phenylmethyl)amino]ethyl] ester, monohydrochloride
CAS Number
54527-84-3
Synonyms
- RS 69216
Molecular Formula
C26H29N3O6 • HCl
Formula Weight
516.0
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS(pH 7.2) (1:2): 0.25 mg/ml
- Ethanol: 1 mg/ml
λmax
236, 352 nm
SMILES
CC1=C(C(C(C(OCCN(CC2=CC=CC=C2)C)=O)=C(N1)C)C3=CC([N+]([O-])=O)=CC=C3)C(OC)=O.Cl
InChi Code
InChI=1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H
InChi Key
AIKVCUNQWYTVTO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17537-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 17537-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 54527-84-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |