Cayman Irak-14 Inhibitor; Purity- Greater Than Or Equal To 98%; S

4-deoxy Pyridoxine (DOP) is a vitamin B₆ antimetabolite with diverse biological activities.^,,,, It inhibits transport of pyridoxine (Item No. ), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells. DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos. It decreases latency to first seizure in mice (ED₅₀ = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy. DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.

WARNING This product is not for human or veterinary use.